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As obesity is closely linked with numerous chronic conditions such as type 2 diabetes, cardiovascular diseases, and certain cancers, there is an increasing urgency among healthcare providers and patients to seek effective treatment options beyond conventional lifestyle modifications

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It is noteworthy that a behavioral analysis of Glp1r +/+ , Glp1r +/ and Glp1r/ mouse phenotypes and hippocampal Glp1r gene transfer demonstrated that deficiency of this receptor results in decrements in the acquisition of associative contextual learning which can be improved by hippocampal Glp1r somatic cell gene transfer [45]

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